Archive forFebruary, 2008
Big Bank Take Little Bank, Part I: Electronic Arts Discusses the Week’s Events Relating to Its Bid For Take-Two
Ever since Electronic Arts made public its intent to acquire Take-Two, newspapers, Web sites and blogs have been abuzz with reporting, rumor and speculation. Over the past couple of days, several business reporters have focused on the recently revised employment contract forTake-Two CEO Strauss Zelnick's ZelnickMedia, which is managing Take-Two. Even though Zelnick admitted to the Wall Street Journal that he originally hadn't planned to remain in the job more than six months, and even though there was significant interest in Take-Two by potential acquirers, ZelnickMedia now has an extra year tacked on to its management contract to go along with an increase in its annual mangement fee from $750,000 to $2.5 million. The Wall Street Journal described the agreement as follows:
Between those two offers [from EA to purhcase Take-Two], on Feb. 14, Take-Two's board of directors approved an amendment to an earlier agreement that more than tripled ZelnickMedia's cash compensation for providing financial and management consulting services to the company, boosting to $2.5 million a year from $750,000 the annual management fee it pays the firm. The board also boosted to $2.5 million from $750,000 the maximum annual bonus the firm is eligible to receive, according to a filing with securities regulators.
The board further granted ZelnickMedia 1.5 million Take-Two restricted shares, worth about $40 million at current prices, an award that still needs to be approved by shareholders at the company's annual meeting. Roughly half of that award will vest immediately if Take-Two is acquired in the near-term and various other conditions are met.
Having speculated on the ramifications of this news earlier in the week, we caught up with Electronic Arts vice president of corporate communications Jeff Brown to see if it had any way impacted EA's plans. Here's what he told us over email:
...(read more)Level Up’s Top Eleven Gaming Tidbits for Feb 29th, 2008 (Leap Day Edition)
- EGO...trip: the Apostrophe Defense Force comes to our rescue
- RUM...ors of PC Gaming's death greatly exaggerated? Or Cliffyb held hostage?
- VSM...on EA/Take-Two, cont'd: "I want big companies to innovate"
- MMO...We can be heroes, for ever and ever...if we plan from the outset
- OUR...milkshake brings all the boys to the yard, says Take-Two...
- BUT...Activision's CEO says he's not one of the boys that are waiting
- SUP...ertoys last all summer long, and other stories of future pets
- SCi...and fourteen of its games go into a room. Only SCi comes out.
- APB...Kotaku puts Phil Harrison on milk carton; videogaming247 finds him
- CDC...may want to investigate the pandemic at this month's GDC
- RND...Random Gawker post comments section taken over, turned into blog
The World’s Growing Food-Price Crisis
If you don't get it yet, please read the implosion article in its entirety. Not merely the titillating excerpts that I quoted. Then, go read The World's Growing Food-Price Crisis at Time.com. I don't believe that the centuries old art of elite gangster macking can be presented in terms any more straight up, simple, or plain. Only difference now, is that the game is international, worldwide...,
"U.S. and British farmers are laughing all the way to the bank,"
says Simon Maxwell, director of the London-based Overseas Development Institute, an independent think tank.
"And some poor people will get jobs on farms or in local communities."
Yet those people will need to buy food, whose prices are rising far faster than wages. With relief agencies struggling to feed the hungry and the shelves in Pakistan, Burkina Faso, Senegal and many other countries in the developing world stocked with food many locals can no longer afford, the prospects for chaos are steadily growing.
The Whole Depraved Mess is Going to Implode
Yielding the floor once again to the devastating power of the hypertiger wisdom;Democracy is just a nice sounding word...You say..."We are in there to give the poor unfortunate people of country X Democracy"...And the population generally appears to accept invasion/conquest without too much resistance.Free your mind....,
But Yes the parliamentary system or Westminster administration system was basically invented by the British...And it works well...The top can maintain control of the bottom but when they lose control and the bottom demands blood...the elected scapegoats take the fall...Not the top...[...]Here it is again...A reminder...
The purpose of the Police and military is to protect the top from the bottom...
To protect cause from consequence...
The easiest prey of the hunter gatherer is the farmer and the simplest operation is the protection scheme...[...]
All money is decreed money...fiat...
The top says this is money...Or else...period end of story....
You Farmer are on the Land owned by the LORD of the land and will pay tribute to the LORD of 1 Gold coin a year...
Where do I get this GOLD coin?
You can take one short ton of grain to the grainery of the LORD and there you will be given a GOLD coin for it and then you can give the gold coin to the servant of the LORD...
What if I refuse?
Then the LORD will drive you from the Land that the LORD is the LORD of...
There you go an abundant supply of free food to power your wildest hopes and dreams...Lies and delusions...[...]
Well what is done with all that Food the tillers of the LORD's land give the LORD as Tribute? It powers the Absolute capitalist Hierarchial food powered make work enterprise...
The city state...Or Civilization...The thing you all popped into existence within...and are in now...
Level Up’s Top Five Gaming Tidbits for Feb 28th, 2008
- DIE...I want you to shoot me as hard as you can
- LOL...Nerd rage-fueled flame wars find an interactive home
- VSM...Corporate games still suck: why Passage is better than Portal
- VSM...EA and T2: "a very bad deal for us" or a move to "competent, stable management"
- RND...Our sister company gets hip. Will Newsweek follow suit? We hope so.
UPDATE: A better link for item #3 can be found here at the blog Grand Text Auto.
...(read more)The Scapegoat is Being Readied

Those managing it are attempting to get to a point where it's planned to fall to pieces...While they are all babbling and creating a smokescreen to obscure the situation the scapegoat is being readied...A mezmerizing spectacle of some sort...to focus attention away from the system as cause and onto an effect as the cause...[...]Be careful what you pay attention to. Not everything that looks good to you is actually good for you.
Behind the scenes the debate currently is between doing what is required to at least keep you all fed (save as many as possible) or just pulling the plug and letting you all starve (Liquidate as many as possible)...and how to deal with the fate resisters.
Behind the scenes they are not wondering if....they know what is coming...The war on terror is just cover to implement all the new crowd controls for the austerity measures that are to follow.
Windows Live Platform News: Microsoft Standardizes on AtomPub for Web Services and Other Stories
David Treadwell has a blog post on the Windows Live Developer blog entitled David Treadwell on New and Updated Windows Live Platform Services where he previews some of the announcements that folks will get to dig into at MIX 08. There are a lot of items of note in his post but there is some stuff that stands out that I felt was worth calling out.
Windows Live Messenger Library (new to beta) – “Develop your own IM experience”
We are also opening up the Windows Live Messenger network for third-party web sites to reach the 300 million+ Windows Live Messenger users. The library is a JavaScript client API , so the user experience is primarily defined by the third party. When a third party integrates the Windows Live Messenger Library into their site they can define the look & feel to create their own IM experience. Unlike the existing third party wrappers for the MSN Protocol (the underlying protocol for Windows Live Messenger) the Windows Live Messenger Library securely authenticates users, therefore their Windows Live ID credentials are safe.
A couple of months ago we announced the Windows Live Messenger IM Control which enables you to embed an AJAX instant messaging window on any webpage so people can start IM conversations with you. I have one placed at http://carnage4life.spaces.live.com and it’s cool to have random readers of my blog start up conversations with me in the middle of my work day or at home via the IM control.
The team who delivered this has been hard at work and now they’ve built a library that enables any developer to build similar experiences on top of the Windows Live Messenger network. Completely customized IM integration is now available for anyone that wants it. Sweet. Kudos to Keiji, Steve Gordon, Siebe and everyone else who had something to do with this for getting it out the door.
An interesting tidbit is that the library was developed in Script#. Three cheers for code generation.
Contacts API (progressed to Beta) – “Bring your friends”
Our goal is to help developers keep users at the center of their experience by letting them control their data and contact portability, while keeping their personal information private. A big step forward in that effort is today’s release to beta of Windows Live Contacts API . Web developers can use this API in production to enable their customers to transfer and share their contacts lists in a secure, trustworthy way (i.e., no more screen scraping)—a great step on the road toward data portability. (For more on Microsoft’s view on data portability, check out Inder Sethi’s video .) By creating an optimized mode for invitations, it allows users to share only the minimum amount of information required to invite friends to a site, this includes firstname / lastname / preferred email address. The Contacts API uses the new Windows Live ID Delegated Authentication framework; you can find out more here .
A lot of the hubbub around “data portability” has really been about exporting contact lists. Those of us working on the Contacts platform at Windows Live realize that there is a great demand for users to be able to access their social graph data securely from non-Microsoft services.
The Windows Live Contacts API provides a way for Windows Live users to give an application permission to access their contact list in Windows Live (i.e. Hotmail address book/Live Messenger buddy list) without giving the application their username and password. It is our plan to kill the password anti-pattern when it comes to Windows Live services. If you are a developer of an application or Web site that screen scrapes Hotmail contacts, I’d suggest taking a look at this API instead of continuing in this unsavory practice.
Atom Publishing Protocol (AtomPub) as the future direction
Microsoft is making a large investment in unifying our developer platform protocols for services on the open, standards-based Atom format ( RFC 4287 ) and the Atom Publishing Protocol ( RFC 5023 ). At MIX we are enabling several new Live services with AtomPub endpoints which enable any HTTP-aware application to easily consume Atom feeds of photos and for unstructured application storage (see below for more details). Or you can use any Atom-aware public tools or libraries, such as .NET WCF Syndication to read or write these cloud service-based feeds.
In addition, these same protocols and the same services are now ADO.NET Data Services (formerly known as “ Project Astoria”) compatible. This means we now support LINQ queries from .NET code directly against our service endpoints, leveraging a large amount of existing knowledge and tooling shared with on-premise SQL deployments.
The first question that probably pops into the mind of regular readers of my blog is, “What happened to Web3S and all that talk about AtomPub not being a general purpose editing format for the Web?”. The fact is when we listened to the community of Web developers the feedback was overwhelmingly clear that people would prefer if we worked together with the community to make AtomPub work for the scenarios we felt it wasn’t suited for than Microsoft creating a competing proprietary protocol.
We listened and now here we are. If you are interested in the technical details of how Microsoft plans to use AtomPub and how we’ve dealt with the various issues we originally had with the protocol. I suggest subscribing to the Astoria team’s blog and check out the various posts on this topic by Pablo Castro. There’s a good post by Pablo discussing how Astoria describes relations between elements in AtomPub and suggests a mechanism for doing inline expansion of links. I’ll be providing my thoughts on each of Pablo’s posts and the responses as I find time during the coming weeks.
Windows Live Photo API (CTP Refresh with AtomPub end point)
The Windows Live Photo API allows users to securely grant permission (via Delegated Authentication) for a third party web site to create/read/update/delete on their photos store in Windows Live. The Photo API refresh has several things which make it easier and faster for third parties to implement.
- Third party web sites can you link/refer to images directly from the web browser so they no longer need to proxy images, and effectively save on image bandwidth bills.
- A new AtomPub end point which makes it even easier to integrate.
At the current time, I can’t find the AtomPub endpoint but that’s probably because the documentation hasn’t been refreshed. Moving the API to AtomPub is one of the consequences of the decision to standardize on AtomPub for Web services provided by Windows Live. Although I was part of the original decision to expose the API using WebDAV, I like the fact that all of our APIs will utilize a standard protocol and can take advantage of the breadth of Atom and AtomPub libraries that exist on various platforms.
I need to track down the AtomPub end point so I can compare and contrast it to the WebDAV version to see what we’ve gained and/or lost in the translation. Stay tuned.
Now playing: Jay-Z - Can't Knock the Hustle
Spaces & SkyDrive: Recent Releases from Windows Live
Over the past week, two Windows Live teams have shipped some good news to their users. The Windows Live SkyDrive team addressed the two most often raised issues with their service with the announcements in their post Welcome to the bigger, better, faster SkyDrive! which reads
You've made two things clear since our first release: You want more space; and you want SkyDrive where you are. Today we're giving you both. You now have five times the space you had before — that’s 5GB of free online storage for your favorite documents, pictures, and other files.
SkyDrive is also available now in 38 countries/regions. In addition to Great Britain, India, and the U.S., we’re live in Argentina, Australia, Austria, Belgium, Bolivia, Brazil, Canada, Chile, Colombia, Denmark, the Dominican Republic, Ecuador, El Salvador, Finland, France, Guatemala, Honduras, Italy, Japan, Mexico, the Netherlands, New Zealand, Nicaragua, Norway, Panama, Paraguay, Peru, Puerto Rico, Portugal, South Korea, Spain, Sweden, Switzerland, Taiwan, and Turkey.![]()
Wow, Windows Live is just drowning our customers with free storage. Thats 5GB in SkyDrive and 5GB for Hotmail.
The Windows Live Spaces team also shipped some sweetness to their customers as well. This feature is a little nearer to my heart since it relies on Contact platform APIs I worked on a little while ago. The feature is described by Michelle in on the their team blog in a post entitled More information on Friends in common which states
In the friends module on another person’s space, there is a new area that highlights friends you have in common. Right away you can see the number of people you both know and the profile pictures of some of those friends.
Want to see the rest of your mutual friends? Click on In common and you’re taken to a full page view that shows all of your friends as well as separate lists of friends in common and friends that you don't have in common. This way you can also discover new people that you might know in real life, but are not connected with on Windows Live.
Finding friends in common is also especially important when planning an event on Windows Live Events . Who wants to go to a party when none of your friends are going?
On the Guest list area of every event, you can now quickly see how many of your friends have also been invited to the event. Just click on See who’s going and see whether or not your friends are planning to go.
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Showing mutual friends as shown above is one of those small features that makes a big impact on the user experience. Nice work Michelle and Shu on getting this out the door.
Now playing: Iconz - I Represent
No Contest: FriendFeed vs. The Facebook News Feed
I found Charles Hudson’s post FriendFeed and the Facebook News Feed - FriendFeed is For Sharing and Facebook Used to be About my Friends somewhat interesting since one of the things I’ve worked on recently is the What’s New page on Windows Live Spaces. He writes
I was reading this article on TechCrunch “ Facebook Targets FriendFeed; Opening Up The News Feed ” and I found it kind of interesting. As someone who uses FriendFeed a lot and uses Facebook less and less, I don’t think the FriendFeed team should spend much time worrying about this announcement. The reason is really simple.
In the beginning, the Facebook News Feed was really interesting. It was all information about my friend and what they were doing. Over time, it’s become a lot less interesting.
…
I would like to see Facebook separate “news” from “activity” - “news” is stuff that happened to people (person x became friend with person y, person x is no longer in a relationship, status updates, etc) and “activities” are stuff related to applications, content sharing, etc. Trying to stuff news and activity into the same channel results in a lot of chaos and noise.FriendFeed is really different. To me, FriendFeed is a community of people who like to share stuff. That’s a very different product proposition than what the News Feed originally set out to do.
This is an example of a situation where I agree with the sentiment in Jeff Atwood’s post I Repeat: Do Not Listen to Your Users. This isn’t to say that Charles Hudson’s increasingly negative user experience with the Facebook should be discounted or that the things he finds interesting about FriendFeed are invalid. The point is that in typical end user fashion, Charles’s complaints contradict themselves and his suggestions wouldn’t address the actual problems he seems to be having.
The main problem Charles has with the news feed on Facebook is its increased irrelevance due to massive amounts of application spam. This has nothing to do with FriendFeed being more of a community site than Facebook. This also has nothing to do with separating “news” from “activity” (whatever that means). Instead it has everything to do with the fact that Facebook platform is an attractive target for applications attempting to “grow virally” to send all sorts of useless crap to people’s friends. Friendfeed doesn’t have that problem because everything that shows up in your feed is pulled from a carefully selected list of services shown below
The thing about the way FriendFeed works is that there is little chance that stuff in the feed would be considered spammy because the content in the feed will always correspond to a somewhat relevant user action (Digging a story, adding a movie to a Netflix queue, uploading photos to Flickr, etc).
So this means one way Facebook can add relevance to the content in their feed is to pull data in from more valid sources instead of relying on spammy applications pushing useless crap like “Dare’s level 17 zombie just bit Rob’s level 12 vampire”.
That’s interesting but there is more. There doesn’t seem to be any tangible barrier to entry in the “market” that Friendfeed is targetting since all they seem to be doing is pulling the public RSS feeds from a handful of Web sites. This is the kind of project I could knock out in two months. The hard part is having a scalable RSS processing platform. However we know Facebook already has one for their feature which allows one to import blog posts as Notes. So that makes it the kind of feature an enterprising dev at Facebook could knock out in a week or two.
The only thing Friendfeed may have going for it is the community that ends up adopting it. The tricky thing about social software is that your users are as pivotal to your success as your features. Become popular with the right kind of users and your site blows up (e.g. MySpace) while with a different set of users your site eventually stagnates due to it’s niche nature (e.g. LiveJournal).
Friendfeed reminds me of Odeo; a project by some formerly successful entrepenuers that tries to jump on a hyped bandwagon without actually scratching an itch that the founders have or fully understanding the space.
Now playing: Jae Millz - No, No, No (remix) (feat. Camron & T.I.)
Dueling Systems and the Five Stages of Collapse
Over the past week and a half or so, I've been chatting with a number of Cobb's commenters and intermittently with the man himself. Here lately, he's embarked on an apologia for war socialism. Brahman has a tendency to get caught up in philosophical rather than practical or empirical argumentation. I've begun to suspect that a significant part of his political orientation is attributable to this tendency. In opting for philosophy and abstraction - both he and his conservative co-religionists have a tendency to get lost in flights of metaphorical fancy.
Case in point yesterday afternoon on a post he called The Morality of War he asked;
"Are you suggesting that we should not have fought Stalin?"Last I checked, we didn't...., but that minor historical quibble aside, this was not a discussion of history, philosophy, or morality per se. Rather, it was the branching of a prior thread in which I was accused of blaming G-Dub for the American war socialist posture. A brief review of Jay Hanson's warsocialism site will clearly dispel any such notions of contemporary blame - and - put the concept of war socialism on its proper historical footing. Hanson calls the system of American governance a war socialist system - I happen to find his arguments concise and very persuasive.
Aside from the countless tragic, wasteful, and destructive proxy wars that it spawned - the political, philosophical and moral dimensions of the Cold War hold little interest for me - I won't be pursuing any of those issues at great length. Rather, what I'd like to bring to your attention is the way in which the former Soviet Union survived it's own economic and industrial collapse - and - invite you to compare and contrast the adaptability and survivability of our own war socialist system of governance in the face of impending collapse. Dmitry Orlov writes;
the collapse of the Soviet Union - our most recent and my personal favorite example of an imperial collapse - did not reach the point of political disintegration of the republics that made it up, although some of them (Georgia, Moldova) did lose some territory to separatist movements. And although most of the economy shut down for a time, many institutions, including the military, public utilities, and public transportation, continued to function throughout. And although there was much social dislocation and suffering, society as a whole did not collapse, because most of the population did not lose access to food, housing, medicine, or any of the other survival necessities. The command-and-control structure of the Soviet economy largely decoupled the necessities of daily life from any element of market psychology, associating them instead with physical flows of energy and physical access to resources. Thus situation, as I argue in my forthcoming book, Reinventing Collapse, allowed the Soviet population to inadvertently achieve a greater level of collapse-preparedness than is currently possible in the United States.IMOHO - this is the type of systematic thinking that we need to enjoin in America as we gird ourselves up to cast what may be operationally and systemically decisive votes in this year's presidential election. I sincerely believe that the U.S. is caught up in a still civil dispute among its ruling elites over the type and pace of contraction and collapse that citizens will be subject to over the next twenty to thirty years. I believe that the frontrunning presidential candidates literally embody the respective elite camps and their dueling perspectives on how this should shake out.
Having given a lot of thought to both the differences and the similarities between the two superpowers - the one that has collapsed already, and the one that is collapsing as I write this - I feel ready to attempt a bold conjecture, and define five stages of collapse, to serve as mental milestones as we gauge our own collapse-preparedness and see what can be done to improve it.
Secrecy, Collusion and Bad Medicine
The drug industry's long and ignoble history of secrecyIn 2004, UK researchers commissioned by Nice to develop guidelines for prescribing antidepressant drugs to children tried to obtain unpublished trials from the drug companies. They were refused. They then contacted the individual researchers who had worked on the trials. Only then did a picture emerge of increased risk of attempted suicide, and a lack of efficacy. Nice concluded by banning the drugs for under-18s with the exception of Prozac.
Yesterday's report suggesting that modern antidepressants offer no significant clinical benefit over placebo has been dismissed by the drug industry as "just one study" which should not be allowed to undermine the wealth of research showing that the selective serotonin reuptake inhibitor (SSRI) antidepressants are effective.
But that is to miss the point. The Hull University researchers have demonstrated how partial access to research can give a distorted view of a drug. The non-disclosure of data on the SSRIs has raised doubts about the trustworthiness of all research on antidepressants.
We should be relieved that the licensing authorities have an absolute right to see all trial data, positive and negative, before approving a drug. But, bizarrely, Nice, with the responsibility for deciding which drugs should be used by the NHS, only gets what the drug companies agree to give it. The Health Select Committee has called for action to remedy this omission. Ministers must respond.
Turn text files into pull down menus
UPDATE: This could also be done with the foreach() construct, but here — on my set-up at least — the for loop is a teensy bit faster.
I developed this PHP function for a project I’m working on. I’m posting it here in case I need it again, or in case you find it handy.
#Input text files must contain one item per line
function print_menu($txtfile_or_files){ $args = func_get_args(); $num_args = func_num_args(); $input = array(); for($i = 0; $i < $num_args; $i++){ // get contents of each text file specified $lines = file($args[$i]); // get each line from each file an add to array for($j = 0; $j < count($lines); $j++){ array_push($input,$lines[$j]); } } // sort alphabetically sort($input,SORT_STRING); for($i = 0; $i < count($input); $i++){ $value = str_replace(' ','_',strtolower(trim($input[$i]))); echo '<option value="'.$value.'">'.trim($input[$i])."</option>\n"; }
}
Configuration and use
The variable $txtfile_or_files should be a comma-separated list of paths to plain text files. This function accepts multiple arguments, in case you want to string multiple files into one menu.
Each text file should contain one item per line. For example:
Red Blue Orange Green
Add another line or two of code if you need to indicate whether the form field value has already been selected.
The Hypocrisy (and Ignorance) of the Music Industry
On March 4-5, Michael McDonald will perform at the Blue Note in New York to celebrate the release of his new album, ‘Soul Speak‘. It’ll be a wonderful day for Michael, but will it be for the ‘Blue Note’?
The ‘Blue Note’ just blogged about Michael’s David Letterman performance which includes an ‘embedded’ YouTube video of the gig. There’s a ton of irony in this: Will technologically incompetent lawyers representing Michael threaten the venue with a “cease and desist” letter laced with false accusations like I received last July?
What the ‘Blue Note’ has done here is no different than several videos I’ve posted to my own site which were ‘embedded’ from YouTube. Unfortunately, I was chastised and chewed up as being the perp who uploaded the videos in question that I ‘embedded’ to my site (There’s a huge difference between ‘linking’ videos and ‘uploading’ them).
The hypocrisy — and ignorance — of an industry that is littered with far too many egos and often bemoans accountability to the very people which make the industry what it is (without ‘fans’, there’s no livelihood for the industry) is more than obvious here.
Chances are, the ‘Blue Note’ won’t be chastised for embedding this video, as they are a paid gig for McD.
To date, I still haven’t received an explanation on the mixup, how I was chosen and how my e-mail address was even known. The last thing in the world I’d do to a friend is cheat him of his rights or harm his brand, product or service by distributing unauthorized works w/o permission (and, no, ‘embedding’ is not ‘distributing’).
Personally, I believe an apology from Vector Management and Michael’s lawyer is long overdue — Michael needn’t be the janitor cleaning up the actions of others (and I did mention this incident to him, and of course, he apologized — But, again, it’s not his doing), for our friendship has been nothing but inspiring over an almost 10 year period.
My only desire is that those representing him should take better precautions to avoid the possibility of alienating those who are friends and supporters of Michael. The music industry continues to demonstrate that they are not in the business of listening — Just dictating (and bullying).
Don’t forget to pick up Michael’s new album, ‘Soul Speak,’ on March 4th:
If you liked this post, how about buying me a coffee?Level Up’s Top Four Gaming Tidbits for Feb 26th, 2008
- EGO...trip: Hate It or Love It? Cool. But this is still How We Do (Fresh '99)
- MTV...goes hog wild on EA's bid for Take-Two. Now, where's Sumner Redstone?
- PS3...maintains its open philosophy when it comes to in-game advertising
- RND...Forgive them, for the Daniel Day-Lewis haters know not what they do
Antidepressant Drugs Don’t Work – Official Study
They are among the biggest-selling drugs of all time, the "happiness pills" that supposedly lift the moods of those who suffer depression and are taken by millions of people in the UK every year.But one of the largest studies of modern antidepressant drugs has found that they have no clinically significant effect. In other words, they don't work.
The finding will send shock waves through the medical profession and patients and raises serious questions about the regulation of the multinational pharmaceutical industry, which was accused yesterday of withholding data on the drugs.
In the study, researchers conducted a meta-analysis of all 47 clinical trials, published and unpublished, submitted to the Food and Drug Administration in the US, made in support of licensing applications for six of the best known antidepressant drugs, including Prozac, Seroxat – which is made by GlaxoSmithKline – and Efexor made by Wyeth. The results showed the drugs were effective only in a very small group of the most extremely depressed.
Two drugs were excluded from the study because of incomplete data. A third drug, chemical name nafazodone, has been withdrawn from the market because of side-effects.
Professor Irving Kirsch of the University of Hull, who led the study published in the online journal Public Library of Science (PLoS) Medicine , said the data submitted to the FDA would also have been submitted to the licensing authorities in Britain and Europe. It showed the drugs produced a "very small" improvement compared with placebo of two points on the 51-point Hamilton depression scale.
That was sufficient to grant the drugs a licence but did not meet the minimum three-point difference required by the National Institute for Clinical Excellence (Nice) to establish "clinical" significance. Full-monty available here - in tomorrow's UK Independent.
I’m Sorry, So Sorry My Dear Companion.
I'm sorry, so sorry I've found a new love. My new love is thinner, prettier and travels better. I tried to bring you to Mobile World Congress and bring you along on that long flight to and fro Spain. I use to bring you with me to work everyday. I would frequently take you to the park or McDonald's as we watched the kids play.
I'm sorry, so sorry. We could sit together and play online day and night provided we brought along a long enough extention cord. We could play videos, listen to music and chat with out friends from around the globe. I could use my Nokia N95 but it isn't the same when we can share such a glorious screen together without straining to see the screen or scroll side to side.
I'm sorry, so sorry. I know I have spent many hours with you, spent hundreds of dollars treating you to all the best money could buy. I have made sure you had everything you have needed in the years we have been together. I even loved you enough to load Linux instead of Windows.
I'm sorry, so sorry I do not spend as much time with you as I once did but I must be honest. I have found a new love. My new love is thinner, prettier and more fun. We can travel everywhere together since we never have to leave each other's side. We go to the movies, out to dinner, road trips and even long airplane rides.
I'm sorry, so sorry. I'm not trying to rub it in but this Nokia N810 does nearly everything I once needed you to do. Yes I will still need you loyal companion. You have served me well and I will use you for those heavy tasks such as video or photo editing, presentations and those longer emails, bigger word processing jobs, uploading or downloading large files, backing up and upgrading the N810. I still need you to store my large music collection and to compress and convert them for the N810 when pressed for space.
I'm sorry, so sorry my dear Thinkpad, your battery life just doesn't cut it. I need something that can last beyond your couple hours of battery life. I can't take lugging you around town, my shoulder just cannot take it. When I had to run from gate to gate at O'Hare, you really weighed me down. Even while I was waiting for the plane at DFW you did have the stamina when the plane was late.
I'm sorry, so sorry. I could say that I would miss your keys, but the N810 has them. I could say I'd miss the touchpad or using the mouse, but the N810 has a touch screen and a stylus. I could say I will miss the maps you have downloaded for me, but the N810 has built-in GPS, free preloadable maps that work even when I don't have WiFi or wireless coverage.
I'm sorry, so sorry. This N810 is so small and lightweight I can put it in my pocket and use it anywhere. On those rare ocassions I must turn it off the N810 boots in a mere fraction of the time. I will miss your larger 15" screen but the 4.13" screen works well also for many tasks. I could go on about the built-in camera, easily expandable and interchangeable MiniSD memory slot and the speedy recharge time but that would be unfair to you, my old faithful companion.
I'm sorry, so sorry my dear Thinkpad. I promise will be more diligent about turning you off, that I might extend your life since I haven't been using you much. I promise I won't forget you and let dust or other things pile up or accumulate a top of you. I promise I will still take you places, even if I leave you in the trunk of the car or hotel room more often.
Your ever loving user,
Matthew Stevens
All We Are Saying - Is Give Kip a Chance…,
Prior to assuming his current position, Ward was Deputy Commander, Headquarters US European Command, Stuttgart, Germany. He previously served as the Deputy Commanding General/Chief of Staff, US Army Europe and Seventh Army. While in this capacity he was selected by the Secretary of State to serve as the United States Security Coordinator, Israel - Palestinian Authority where he served from March through December 2005.If you have concerns, take them directly to the Africom Dialogue A clearinghouse of the U.S. Africa Command's senior leader's updates on issues important at AFRICOM. We encourage your comments and feedback.
How to Get Bloggers to Talk About Your Business
If you’re a public relations professional–or an above-average entrepreneur–you’ve probably wondered how you can get bloggers to talk about your business…in a favorable way.
Late last year, I was a guest speaker on a webinar that was geared toward PR agents. Prior to that I had had extensive conversations with business owners and PR pros about social media–and most honestly admitted they had no idea how to make social media work for them. They saw it as this black hole of yet more new technology that wasn’t going away as previously thought but, in fact, was taking the world by storm.
During my speaking tour last year a frustrated woman actually asked, “Who are these bloggers? What do they want from us? What drives them? Why do they care?”
Truthfully, most companies DO get it all wrong and end up angering the bloggers with whom they want to become allies. But, you? You’re lucky…you know me and you read this blog. That doesn’t have to happen to you.
That’s why I wrote The Blogosphere Cluebook–to show you, step-by-step, both what to do and what NOT to do when befriending bloggers. It’s not the War and Peace on social media influencers by a long shot, but it will serve as a bit of a North Star in the confusing world of widgets and wikis.
The book is free to download, post on your site or blog or e-mail to colleagues and friends.
